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Abnormal levels of tryptophan can therefore negatively impact immune responses, metabolic stress pathways, and brain function, leading to a wide range of symptoms associated with ME/CFS and FM (Gostner et al., 2020)

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However, the fact that there have been fewer studies on the treatment of UC with different probiotics coupled with selected prebiotics, i.e., synbiotics, and the outcomes of these studies have been very favorable