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The concentration of GSH, γ-L-glutamyl-L-cysteinyl-glycine, which is the most abundant non-protein thiol in cells, is in the range of 1–10 mM in most mammalian cells [12]
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By blocking NNMT, 5-amino-1MQ promotes an increase in nicotinamide adenine dinucleotide (NAD+), a cofactor essential for cellular metabolism
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